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Article Review / Estimating the Tumoral Half-life of Fluorouracil

Abstract: 5 page explication of a 1994 journal article in which the authors assess the association of intratumoral pharmacokinetics of fluorouracil with clinical response. Built upon was existing research which had established that In-vivo flouring-19 nuclear magnetic resonance spectroscopy (NMRS) facilitates non-invasive, immediate, chemical identification of distinct fluorinated compounds within tumors found in humans after flouorouracil is given. The authors of the discussed study employ kinetic measures of the drug administered as well as metabolies to estimate the tumoral half-life of fluorouracil. No Bibliography.


Catagory: Disease, Treatment, & Epidemiology

Subcatagory: Medicine, Medical Issues, & Pharmacy


 

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